Development of in vitro test systems for hepatotoxicity and cardiotoxicity
based on human embryonic derived stem cells
 

Satellite meeting to ESTIV2008 – 15th International Congress on In Vitro Toxicology, September 24, Djurönäset Conference Center, Stockholm

The satellite meeting is organised by the EU-projects Vitrocellomics and Invitroheart in collaboration with the organisers of ESTIV2008.

 

9.00 – 9.15
Welcome address. Carl-Fredrik Mandenius, Linköping University

9.15 – 10.00
hESC for toxicology and metabolic applications. Gabriela Cezar, University of Wisconsin

10.00 -10.30
Human embryonic stem cell-derived cardiomyocytes: state-of-the-art functionality and applications. Peter Sartipy, Cellartis AB

10.30 -11.00
Coffee

11.00 – 11.30
Human embryonic stem cell-derived hepatocytes: state-of-the-art functionality and applications. Barbara Küppers-Munther, Cellartis AB

11.30 – 12.00
Development of 3D-bioreactor test systems for hepatotoxicity and metabolism. Katrin Zeilinger, Charité University Hospital, Berlin

12.00 – 12.30
Optimization of stem cell differentiation protocols by chemometric modeling. Carl-Fredrik Mandenius, Linköping University

12.30 – 14.00
Lunch

14.00 – 14.45
To be announced.

14.45 – 15.15
Assessment of drug-induced QT-prolongation by multi-electrode arrays. Udo Kraushaar,
NMI, Tubingen University

15.15 – 15.45
Detection of toxic effects by monitoring metabolic processes. Fozia Noor, Saarland University

15.45 – 16.15
Coffee

16.15 – 16.45
Methods employed by CROs for detection of cytotoxic effects. Reiner Class, Pharmacelsus GmbH

16.45 – 17.15
Interindividual variability in xenobiotic metabolism. Inger Johansson, Karolinska Institute

17.15 – 18.00
Panel discussion

18.00
Closing of the satellite meeting

19:00
Dinner